Journal: The Journal of Biological Chemistry

Article Title: Laccaic Acid A Is a Direct, DNA-competitive Inhibitor of DNA Methyltransferase 1 *

doi: 10.1074/jbc.M113.480517

Figure Lengend Snippet: qPCR validation of LCA microarray analysis and changes in gene expression caused by treatment with control compound, anthraquinone-2-carboxylic acid

Article Snippet: Microarray Analysis Total RNA was isolated from 2 × 10 5 cells and used for microarray analysis (University of Iowa DNA Core Facility) in hybridization to Human Gene ST1.0 Array GeneChips (Affymetrix).

Techniques: Biomarker Discovery, Microarray, Gene Expression, Control

Journal: Frontiers in Genetics

Article Title: Distinct Associations of BMI and Fatty Acids With DNA Methylation in Fasting and Postprandial States in Men

doi: 10.3389/fgene.2021.665769

Figure Lengend Snippet: Selected 5′ region dmCpG associated with multiple FA.

Article Snippet: Interestingly, we previously found that HIVEP3 cg23762517 and cg26038582 methylation correlated inversely with expression in THP-1 cells stimulated with OA in the 1–10-μM range ( r = −0.61; Affymetrix Human Exon 1.0 ST data and 450K data), thus mirroring the positive association of OA with HIVEP3 promoter dmCpG observed here ( ).

Techniques: Activity Assay